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{"id":8695,"date":"2023-01-07T10:32:00","date_gmt":"2023-01-07T09:32:00","guid":{"rendered":"https:\/\/test.eneviahealth.com\/?p=8695"},"modified":"2025-01-03T18:39:41","modified_gmt":"2025-01-03T17:39:41","slug":"un-dano-congenito-del-nervio-auditivo-se-relaciona-con-los-trastornos-del-espectro-autista","status":"publish","type":"post","link":"https:\/\/test.eneviahealth.com\/en\/blog\/un-dano-congenito-del-nervio-auditivo-se-relaciona-con-los-trastornos-del-espectro-autista\/","title":{"rendered":"Congenital auditory nerve damage linked to autism spectrum disorders"},"content":{"rendered":"<p><strong>A rather unique feature of autism spectrum disorders is that many of the patients who suffer from them tend to show increased sensitivity to sound. When this phenomenon has been investigated, the majority trend has been to investigate the brain.<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-1024x683.jpg\" alt=\"\" class=\"wp-image-8696\" srcset=\"https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-1024x683.jpg 1024w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-300x200.jpg 300w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-768x512.jpg 768w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-1536x1024.jpg 1536w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-2048x1365.jpg 2048w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-18x12.jpg 18w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-1320x880.jpg 1320w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/pediatrician-examining-child-ear-with-otoscope-in-2022-04-12-23-53-03-utc-500x333.jpg 500w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>However, it seems that the answer may not lie in this organ, but rather in the peripheral nervous system. And it is that a team of researchers from the Medical University of South Carolina has found a certain hearing loss and&nbsp;<strong>mild damage to the auditory nerve<\/strong>&nbsp;in a preclinical model of autism spectrum disorders.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Amplified sensitivity to auditory signals<\/h2>\n\n\n\n<p id=\"m112-111-113\">More specifically, they detail in the specialized medium&nbsp;<em><a href=\"https:\/\/www.jneurosci.org\/content\/42\/42\/8002\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Journal of Neuroscience<\/em><\/a><\/em><em>,&nbsp;<\/em>a thorough examination of the auditory nerve revealed abnormal supporting cells, called glia,&nbsp;<strong>degeneration similar to that produced by age<\/strong>and inflammation. These findings underscore the importance of considering sensory organs and their interactions with the brain when understanding these types of disorders.<\/p>\n\n\n\n<p>These conclusions are conclusive with previous work that had found that age-related hearing loss could cause the brain to<strong>increase your response to reduced signals<\/strong>&nbsp;as a compensatory mechanism. In fact, the authors were trying to figure out if this dynamic might be behind the increased sensitivity in patients with autism spectrum disorders.<\/p>\n\n\n\n<p id=\"m157-156-158\">To do this, they created&nbsp;<strong>preclinical models<\/strong>, genetically engineering mice to have only one working copy of the MEF2C gene, which is known to cause behaviors and symptoms consistent with autism spectrum disorders.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-1024x683.jpg\" alt=\"\" class=\"wp-image-8698\" srcset=\"https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-1024x683.jpg 1024w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-300x200.jpg 300w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-768x512.jpg 768w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-1536x1024.jpg 1536w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-2048x1365.jpg 2048w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-18x12.jpg 18w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-1320x880.jpg 1320w, https:\/\/test.eneviahealth.com\/wp-content\/uploads\/2023\/01\/unruly-angry-girl-covering-her-ears-and-looking-at-2022-12-16-08-48-29-utc-1-500x333.jpg 500w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">The importance of sensory organs<\/h2>\n\n\n\n<p id=\"m167-166-168\">First of all,&nbsp;<strong>measured the brain&#039;s response<\/strong>to auditory cues using a modified version of a test commonly used to measure hearing loss in newborn babies. In this way, they were able to verify that the modified mice did indeed show a certain loss of hearing compared to the control group.<\/p>\n\n\n\n<p>Subsequently, they measured the&nbsp;<strong>auditory nerve activity<\/strong>, which carries signals from the inner ear to the brain and analyzed in detail the nervous tissue, finding damage similar to that produced by age.<\/p>\n\n\n\n<p id=\"m211-210-212\">What is remarkable, however, is that while the brain&#039;s response to auditory signals was only slightly less than that seen in healthy mice, the nerve damage was very significant. This implies that, indeed, the brain&nbsp;<strong>increases your sensitivity<\/strong>&nbsp;as a mechanism to compensate for this problem.<\/p>\n\n\n\n<p id=\"m216-215-217\">Although the relationship between this hearing loss and the disorder cannot yet be considered definitive, these researchers believe that it is illustrative of how certain&nbsp;<strong>congenital sensory disorders<\/strong>or in the early stages of life, they could be influencing brain development and, perhaps, the genesis of certain disorders.<\/p>\n\n\n\n<p>\u2705 Source of information&nbsp;<a href=\"https:\/\/www.20minutos.es\/salud\/actualidad\/un-dano-congenito-del-nervio-auditivo-se-relaciona-con-los-trastornos-del-espectro-autista-5088127\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.20minutos.es\/salud\/actualidad\/un-dano-congenito-del-nervio-auditivo-se-relaciona-con-los-trastornos-del-espectro-autista-5088127\/<\/a><\/p>\n\n\n\n<p>\ud83d\udccc Visit us through<\/p>\n\n\n\n<p>Web:&nbsp;<a href=\"https:\/\/test.eneviahealth.com\/en\/\">https:\/\/test.eneviahealth.com<\/a><\/p>\n\n\n\n<p>Youtube:&nbsp;<a href=\"https:\/\/www.youtube.com\/c\/EneviaHealthSL\" target=\"_blank\" rel=\"noopener\">https:\/\/www.youtube.com\/c\/EneviaHealthSL<\/a><\/p>\n\n\n\n<p>Facebook:&nbsp;<a href=\"https:\/\/www.facebook.com\/eneviahealth\" target=\"_blank\" rel=\"noopener\">https:\/\/www.facebook.com\/eneviahealth<\/a><\/p>\n\n\n\n<p>Instagram:&nbsp;<a href=\"https:\/\/www.instagram.com\/enevia_health\/\" target=\"_blank\" rel=\"noopener\">@enevia_health<\/a><\/p>\n\n\n\n<p>#fraa #frat #frattest #autismo #neurodesarrollo #neurodesarrolloinfantil #autismoinfantil #autismoSpain #eneviahealth<\/p>","protected":false},"excerpt":{"rendered":"<p>Una caracter\u00edstica bastante particular de los trastornos del espectro autista es que muchos de los pacientes que los padecen tienden a mostrar una&nbsp;sensibilidad aumentadahacia el sonido. Cuando se ha investigado este fen\u00f3meno, la tendencia mayoritaria ha sido indagar en el cerebro. Sin embargo, parece ser que la respuesta podr\u00eda no estar en este \u00f3rgano, sino [&hellip;]<\/p>\n","protected":false},"author":1501,"featured_media":114999,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[165],"tags":[],"class_list":["post-8695","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tea"],"_links":{"self":[{"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/posts\/8695","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/users\/1501"}],"replies":[{"embeddable":true,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/comments?post=8695"}],"version-history":[{"count":1,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/posts\/8695\/revisions"}],"predecessor-version":[{"id":115035,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/posts\/8695\/revisions\/115035"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/media\/114999"}],"wp:attachment":[{"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/media?parent=8695"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/categories?post=8695"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/test.eneviahealth.com\/en\/wp-json\/wp\/v2\/tags?post=8695"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}