DNA methylation pathway profiling is a tool that allows clinicians to identify single nucleotide polymorphisms (SNPs) that may affect critical biochemical pathways such as methionine metabolism, detoxification, hormonal balance, and cell function. vitamin D. SNPs can affect disease risk and their identification can help optimize health and wellness outcomes for patients. By recommending lifestyle changes and dietary supplements, doctors can help patients reduce the risk of developing disease and support optimal functioning of metabolic pathways.
Why request a microbiology test?
Detection of single nucleotide polymorphisms (SNPs) that can affect health and disease risk is crucial to delivering effective clinical care to patients. DNA methylation pathway profiling can identify several SNPs associated with many aspects of health, including insulin sensitivity, bone health, cancer risks, cardiovascular health, detoxification processes, fertility, mitochondrial function, metabolism, methylation, and neurotransmitter balance. These SNPs are DNA sequence variations that commonly occur in the general population and can affect the structure and function of cellular proteins, enzymes, or receptors. The identification of SNPs and their impact on health is an active area of research that has the potential to lead to more personalized medical interventions.
Interpretation of SNP results can be challenging, as it can be difficult to determine to what extent a DNA genotype is expressed phenotypically. Functional tests, along with assessment of a patient's symptoms and responses to intervention, are essential to assess the influence of known SNPs on the phenotype.
How could you benefit from this test?
Several single nucleotide polymorphisms are known to influence many aspects of health, including:
- bone health
- cancer risks
- Cardiovascular health
- detox
- Fertility
- insulin sensitivity
- methylation
- Mitochondrial function and metabolism
- neurotransmitter balance
Report
The DNA Methylation Profile report assists in clinical support of patients by identifying SNPs that could potentially impact health and disease risk.
Analytes
DNA methylation profiling identifies 30 SNPs that may influence health and disease risk:
- ACAT – 1-02
- AHCY – 19
- AHCY-1
- AHCY-2
- BHMT – 1
- BHMT – 2
- BHMT-4
- BHMT-8
- CBS-A360A
- CBS-C699T
- CBS-N212N
- COMT-61
- COMT–H62H
- COMT-V158M
- MAO A-R297R
- MTHFR–3
- MTHFR-A1298C
- MTHFR-C677T
- MTR-A2756G
- TMR-11
- MTRR-A66G
- MTRR-H595Y
- MTRR-K350A
- MTRR-R415T
- MTRR-S257T
- NOS – D298E
- SHMT-C1420T
- SUOX-S370S
- VDR–Fok1
- VDR-Taq1
